Pseudomonas aeruginosa F9676, ADJ52_RS21340 (hscA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016226 iron-sulfur cluster assembly
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006457 protein folding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140662 ATP-dependent protein folding chaperone
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR19375
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051082 unfolded protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR19375 HEAT SHOCK PROTEIN 70KDA IPR013126 Heat shock protein 70 family 21 548 7.9E-128
SUPERFAMILY SSF53067 Actin-like ATPase domain IPR043129 ATPase, nucleotide binding domain 19 197 1.72E-51
Gene3D G3DSA:3.30.420.40 - - - 22 374 1.7E-121
Hamap MF_00679 Chaperone protein HscA [hscA]. IPR010236 ISC system FeS cluster assembly, HscA chaperone 1 617 45.471146
FunFam G3DSA:3.30.420.40:FF:000046 Chaperone protein HscA - - 22 205 4.4E-64
Gene3D G3DSA:1.20.1270.10 - IPR029048 Heat shock protein 70kD, C-terminal domain superfamily 520 616 2.7E-28
PRINTS PR00301 70kDa heat shock protein signature - - 152 172 2.4E-56
Gene3D G3DSA:2.60.34.10 Substrate Binding Domain Of DNAk; Chain A, domain 1 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily 379 517 1.0E-48
FunFam G3DSA:2.60.34.10:FF:000005 Chaperone protein HscA homolog - - 380 519 2.1E-80
SUPERFAMILY SSF100920 Heat shock protein 70kD (HSP70), peptide-binding domain IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily 384 535 2.75E-50
Gene3D G3DSA:3.90.640.10 Actin; Chain A, domain 4 - - 238 311 1.7E-121
PRINTS PR00301 70kDa heat shock protein signature - - 329 345 2.4E-56
PRINTS PR00301 70kDa heat shock protein signature - - 360 380 2.4E-56
SUPERFAMILY SSF53067 Actin-like ATPase domain IPR043129 ATPase, nucleotide binding domain 200 376 1.57E-47
PRINTS PR00301 70kDa heat shock protein signature - - 48 60 2.4E-56
PRINTS PR00301 70kDa heat shock protein signature - - 20 33 2.4E-56
Gene3D G3DSA:3.30.420.40 - - - 194 361 1.7E-121
Pfam PF00012 Hsp70 protein IPR013126 Heat shock protein 70 family 21 600 0.0
CDD cd10236 HscA_like_NBD IPR042039 HscA chaperone, nucleotide-binding domain 20 375 0.0
PRINTS PR00301 70kDa heat shock protein signature - - 466 482 2.4E-56
PRINTS PR00301 70kDa heat shock protein signature - - 385 404 2.4E-56
NCBIfam TIGR01991 JCVI: Fe-S protein assembly chaperone HscA IPR010236 ISC system FeS cluster assembly, HscA chaperone 21 616 0.0
SUPERFAMILY SSF100934 Heat shock protein 70kD (HSP70), C-terminal subdomain IPR029048 Heat shock protein 70kD, C-terminal domain superfamily 504 615 2.75E-33
Coils Coil Coil - - 526 546 -
PRINTS PR00301 70kDa heat shock protein signature - - 211 221 2.4E-56

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.