Pseudomonas aeruginosa DSM 50071, TU83_RS07535

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01627
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 1754 1781 -
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1758 2473 0.0
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1994 2175 7.99E-36
Coils Coil Coil - - 1372 1392 -
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2183 2322 1.2E-22
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 866 963 3.8E-6
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1045 1131 2.5E-11
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1364 1461 6.6E-7
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1366 1459 6.7E-14
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 868 955 1.6E-13
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.0E-8
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1993 2177 1.7E-60
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1524 1653 3.6E-27
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1671 1768 6.4E-4
MobiDBLite mobidb-lite consensus disorder prediction - - 989 1037 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1673 1766 3.9E-15
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1524 1622 5.52773E-15
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 2258 2318 2.9E-19
SMART SM00260 chew_2 IPR002545 CheW-like domain 2170 2320 2.0E-34
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1364 1494 5.1E-29
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2138 2156 1.5E-10
Coils Coil Coil - - 1891 1911 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 866 962 3.98429E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 433 556 1.94E-14
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1991 2177 1.0E-52
MobiDBLite mobidb-lite consensus disorder prediction - - 565 618 -
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1524 1621 0.0095
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1186 1306 1.91E-15
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1037 1172 3.3E-18
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1364 1462 3.2672E-15
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1043 1146 0.49
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 2355 2466 3.07832E-30
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 2177 2316 1.7E-21
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1625 4.7E-14
Gene3D G3DSA:3.40.50.2300 - - - 2355 2474 5.3E-40
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 866 991 4.6E-27
CDD cd16916 HATPase_CheA-like - - 2000 2175 1.21249E-83
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 2353 2466 2.9E-37
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1043 1166 4.84E-19
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2355 2467 1.6E-27
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1672 1780 4.19E-20
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2162 2175 1.5E-10
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1043 1134 2.00715E-5
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1665 1798 3.3E-23
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1187 1314 8.6E-14
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2041 2177 1.8E-16
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 866 996 4.5E-28
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 137 1.3E-11
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1364 1486 1.83E-27
MobiDBLite mobidb-lite consensus disorder prediction - - 658 681 -
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 2037 2178 1.3E-22
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1524 1646 1.83E-26
Coils Coil Coil - - 232 252 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1672 1776 5.32693E-13
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1853 1992 1.3E-11
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.83E-23
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 2352 2471 3.98E-36
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2082 2096 1.5E-10

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.