Pseudomonas aeruginosa LESB58, PALES_53651 (aruI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02776
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.970 - - - 384 558 6.8E-39
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 221 350 3.5E-28
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 22 204 3.78E-53
Coils Coil Coil - - 558 559 -
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 386 557 8.04E-42
Gene3D G3DSA:3.40.50.1220 - - - 216 383 1.5E-38
CDD cd00568 TPP_enzymes - - 388 554 1.04839E-45
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 31 199 2.4E-53
Gene3D G3DSA:3.40.50.970 - - - 20 206 1.6E-55
PANTHER PTHR18968 THIAMINE PYROPHOSPHATE ENZYMES IPR045229 Thiamine pyrophosphate enzyme 29 553 6.3E-125
FunFam G3DSA:3.40.50.970:FF:000084 Probable 2-ketoarginine decarboxylase AruI - - 24 204 1.4E-119
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, TPP-binding 414 552 1.7E-27
SUPERFAMILY SSF52467 DHS-like NAD/FAD-binding domain IPR029035 DHS-like NAD/FAD-binding domain superfamily 184 377 9.82E-38
CDD cd07035 TPP_PYR_POX_like - - 34 190 5.10723E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.