Pseudomonas aeruginosa LESB58, PALES_41651 (nrdA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0005971	ribonucleoside-diphosphate reductase complex	ISS Inferred from Sequence or Structural Similarity Term mapped from: PseudoCAP:PA1156	ECO:0000249 sequence similarity evidence used in automatic assertion	16829681
Biological Process	GO:0006260	DNA replication	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00317	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other LESB58 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Pyrimidine metabolism		ECO:0000037 not_recorded
PseudoCAP		Purine metabolism		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	760	787	4.3E-48
CDD	cd01679	RNR_I	-	-	319	907	0.0
Gene3D	G3DSA:3.20.70.20	-	-	-	220	915	0.0
PANTHER	PTHR11573	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN	IPR039718	Ribonucleoside-diphosphate reductase large subunit	150	963	0.0
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	1	23	-
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	618	641	4.3E-48
Pfam	PF03477	ATP cone domain	IPR005144	ATP-cone domain	149	233	8.3E-8
Pfam	PF02867	Ribonucleotide reductase, barrel domain	IPR000788	Ribonucleotide reductase large subunit, C-terminal	371	906	0.0
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	446	465	4.3E-48
SUPERFAMILY	SSF51998	PFL-like glycyl radical enzymes	-	-	370	907	0.0
Pfam	PF00317	Ribonucleotide reductase, all-alpha domain	IPR013509	Ribonucleotide reductase large subunit, N-terminal	294	365	7.6E-22
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	581	592	4.3E-48
Pfam	PF03477	ATP cone domain	IPR005144	ATP-cone domain	33	128	2.8E-18
SUPERFAMILY	SSF48168	R1 subunit of ribonucleotide reductase, N-terminal domain	IPR008926	Ribonucleotide reductase R1 subunit, N-terminal	154	369	4.45E-64
FunFam	G3DSA:3.20.70.20:FF:000009	Ribonucleoside-diphosphate reductase	-	-	219	915	0.0
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	656	678	4.3E-48
NCBIfam	TIGR02506	JCVI: ribonucleoside-diphosphate reductase subunit alpha	IPR013346	Ribonucleotide reductase, class I, alpha subunit, C-terminal	297	907	0.0
PRINTS	PR01183	Ribonucleotide reductase large chain signature	IPR000788	Ribonucleotide reductase large subunit, C-terminal	684	707	4.3E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.