Pseudomonas aeruginosa LESB58, PALES_24791 (mnmA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0008033 tRNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01998
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016740 transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01998
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016783 sulfurtransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.30.280
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF20258 Aminomethyltransferase beta-barrel domain IPR046885 tRNA-specific 2-thiouridylase MnmA-like, C-terminal domain 289 363 7.7E-22
Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. IPR004506 tRNA-specific 2-thiouridylase 11 364 40.513153
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 11 248 6.62E-57
FunFam G3DSA:2.40.30.10:FF:000023 tRNA-specific 2-thiouridylase MnmA - - 286 369 1.9E-29
Pfam PF20259 tRNA methyl transferase PRC-barrel domain IPR046884 tRNA-specific 2-thiouridylase MnmA-like, central domain 212 279 1.6E-23
Gene3D G3DSA:2.30.30.280 - IPR023382 tRNA-specific 2-thiouridylase MnmA-like, central domain superfamily 217 285 1.7E-25
Gene3D G3DSA:2.40.30.10 Translation factors - - 286 370 2.4E-27
FunFam G3DSA:3.40.50.620:FF:000004 tRNA-specific 2-thiouridylase MnmA - - 5 216 3.4E-117
Pfam PF03054 tRNA methyl transferase HUP domain - - 12 207 8.1E-82
FunFam G3DSA:2.30.30.280:FF:000001 tRNA-specific 2-thiouridylase MnmA - - 217 284 2.8E-24
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 2 216 1.4E-93
CDD cd01998 tRNA_Me_trans IPR004506 tRNA-specific 2-thiouridylase 12 363 0.0
NCBIfam TIGR00420 JCVI: tRNA 2-thiouridine(34) synthase MnmA IPR004506 tRNA-specific 2-thiouridylase 12 363 0.0
PANTHER PTHR11933 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE - - 10 364 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.