Pseudomonas aeruginosa LESB58, PALES_09691 (proA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.605.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other LESB58 genes in this class
Amino acid biosynthesis and metabolism Other LESB58 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Porphyrin and chlorophyll metabolism ECO:0000037
not_recorded
PseudoCAP Urea cycle and metabolism of amino groups ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 14 284 7.3E-14
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 8 420 1.05E-121
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 15 417 0.0
Coils Coil Coil - - 35 55 -
PANTHER PTHR11063 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE - - 5 420 0.0
CDD cd07079 ALDH_F18-19_ProA-GPR IPR000965 GPR domain 52 416 0.0
PIRSF PIRSF000151 GPR IPR012134 Glutamate-5-semialdehyde dehydrogenase 1 421 0.0
FunFam G3DSA:3.40.309.10:FF:000006 Gamma-glutamyl phosphate reductase - - 229 378 2.2E-60
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 229 378 0.0
NCBIfam TIGR00407 JCVI: glutamate-5-semialdehyde dehydrogenase IPR000965 GPR domain 16 410 0.0
Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. IPR000965 GPR domain 8 420 42.748184
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 312 377 2.1E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.