Pseudomonas aeruginosa NCGM1900, NCGM1900_RS31305

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paeb02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 542 552 5.0E-19
SMART SM00091 pas_2 IPR000014 PAS domain 256 321 1.2E-5
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 555 573 5.0E-19
Gene3D G3DSA:3.30.450.20 PAS domain - - 245 362 1.4E-16
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 524 538 5.0E-19
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 358 441 1.22E-15
SMART SM00304 HAMP_11 IPR003660 HAMP domain 193 245 4.1E-12
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 430 593 2.75E-46
FunFam G3DSA:3.30.565.10:FF:000006 Sensor histidine kinase WalK - - 446 593 2.2E-39
Gene3D G3DSA:1.10.8.500 HAMP domain in histidine kinase - - 192 243 7.4E-9
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 445 593 3.1E-46
CDD cd00130 PAS IPR000014 PAS domain 265 364 8.68472E-6
PANTHER PTHR44936 SENSOR PROTEIN CREC - - 3 592 0.0
CDD cd19409 KinB_sensor IPR031909 Alginate biosynthesis sensor protein KinB, sensor domain 45 155 3.32399E-38
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 579 592 5.0E-19
Pfam PF16767 Sensor domain of alginate biosynthesis sensor protein KinB IPR031909 Alginate biosynthesis sensor protein KinB, sensor domain 40 158 9.5E-39
SUPERFAMILY SSF158472 HAMP domain-like - - 193 243 3.79E-8
Gene3D G3DSA:1.20.120.880 Histidine kinase (KinB), sensor domain IPR038320 KinB, N-terminal domain superfamily 37 166 7.1E-36
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 373 441 1.1E-16
Pfam PF00672 HAMP domain IPR003660 HAMP domain 191 242 1.5E-11
CDD cd00075 HATPase - - 492 591 5.36474E-37
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 374 441 6.8E-12
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 371 437 2.3377E-12
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 244 365 1.66E-13
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 489 592 3.0E-24
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 255 371 3.4E-7
Pfam PF08448 PAS fold IPR013656 PAS fold-4 262 368 9.5E-11
CDD cd06225 HAMP - - 198 240 3.22498E-9
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 487 593 7.3E-33
Gene3D G3DSA:1.10.287.130 - - - 363 443 2.6E-15

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.