Pseudomonas aeruginosa PAO581, M801_5035 (msbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0140359 ABC-type transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02203
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0034040 ATPase-coupled lipid transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02203
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00005
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paeo02010 ABC transporters 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd03251 ABCC_MsbA - - 356 590 0.0
Gene3D G3DSA:1.20.1560.10 ABC transporter type 1, transmembrane domain IPR036640 ABC transporter type 1, transmembrane domain superfamily 6 342 1.2E-69
Pfam PF00005 ABC transporter IPR003439 ABC transporter-like, ATP-binding domain 373 523 1.6E-32
NCBIfam TIGR02203 JCVI: lipid A export permease/ATP-binding protein MsbA IPR011917 ABC transporter, lipid A-core flippase, MsbA 15 595 0.0
CDD cd18552 ABC_6TM_MsbA_like - - 30 332 4.01983E-105
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 382 575 4.2E-17
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 346 591 1.33E-94
Pfam PF00664 ABC transporter transmembrane region IPR011527 ABC transporter type 1, transmembrane domain 31 306 1.7E-48
PANTHER PTHR24221 ATP-BINDING CASSETTE SUB-FAMILY B IPR039421 Type 1 protein exporter 85 589 0.0
SUPERFAMILY SSF90123 ABC transporter transmembrane region IPR036640 ABC transporter type 1, transmembrane domain superfamily 18 338 3.4E-71
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 343 593 2.1E-93
FunFam G3DSA:3.40.50.300:FF:000140 Lipid A export ATP-binding/permease protein MsbA - - 347 596 8.7E-107

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.