Pseudomonas aeruginosa C7447m, M802_1568 (ligA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00532
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paec03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paec03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paec03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paec03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 330 412 3.26E-28
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 3 328 3.6E-118
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 714 788 5.23E-17
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 702 788 2.0E-23
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 68 327 6.3E-98
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 16 770 2.0E-55
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 330 8.4E-124
CDD cd17748 BRCT_DNA_ligase_like - - 716 786 2.31593E-24
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 454 529 3.4E-30
Gene3D G3DSA:1.10.150.20 - - - 624 701 1.3E-11
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 530 609 3.4E-25
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 329 402 9.4E-35
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 2.6E-29
SMART SM00292 BRCT_7 IPR001357 BRCT domain 713 790 6.3E-9
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 419 458 1.4E-13
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 67 8.2E-29
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 334 410 6.7E-35
Gene3D G3DSA:1.10.150.20 - - - 454 528 3.0E-28
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 620 792 2.3E-31
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 534 597 7.3E-21
FunFam G3DSA:3.40.50.10190:FF:000069 DNA ligase - - 706 789 8.8E-42
Gene3D G3DSA:6.20.10.30 - - - 403 453 2.4E-13
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 622 0.0
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 327 4.8E-107
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 472 0.0
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 713 787 2.2E-11
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 329 0.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 329 402 3.3E-33
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 632 687 2.4E-8
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 416 603 1.04E-52
Gene3D G3DSA:1.10.150.20 - - - 529 611 1.9E-24
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 618 704 7.78E-14
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 787 52.847733
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 616 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.