Pseudomonas mandelii JR-1, OU5_RS19300

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01584
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47226
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pman02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pman02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 630 756 0.0
CDD cd16916 HATPase_CheA-like - - 1507 1682 2.70093E-76
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1072 1161 1.4E-14
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1498 1684 2.3E-51
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1212 1332 1.7E-28
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 766 863 1.9E-4
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1845 1958 9.6E-36
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1500 1684 1.3E-58
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 770 853 2.9E-11
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1070 1168 1.02636E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 767 889 1.83E-18
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 129 8.5E-10
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 627 711 1.87505E-8
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1212 1340 1.2E-30
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 1544 1685 2.6E-23
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 4.71E-21
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 909 1035 3.1E-12
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1669 1682 6.0E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 629 719 6.0E-14
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 1690 1819 4.5E-21
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1844 1962 1.32E-36
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1501 1682 1.3E-35
Pfam PF02895 Signal transducing histidine kinase, homodimeric domain IPR004105 Histidine kinase CheA-like, homodimeric domain 1362 1498 1.1E-5
Coils Coil Coil - - 1461 1484 -
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1847 1958 8.5439E-32
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 769 895 8.8E-16
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1212 1309 8.1E-9
Gene3D G3DSA:3.40.50.2300 - - - 1847 1966 8.2E-40
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1070 1167 1.0E-7
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1069 1201 2.8E-29
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1360 1499 1.1E-11
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 627 764 8.6E-29
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1589 1603 6.0E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1214 1314 8.7E-15
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 1548 1684 6.0E-14
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 432 556 3.0E-14
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 96 7.5E-6
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1212 1310 1.59101E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 627 750 9.94E-28
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1645 1663 6.0E-10
Coils Coil Coil - - 67 87 -
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 627 724 1.7E-7
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 770 836 8.50363E-8
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 908 1030 1.35E-14
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 1684 1817 2.09E-22
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 1759 1819 8.7E-20
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1070 1192 6.28E-29
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1847 1958 1.0E-26
Coils Coil Coil - - 1391 1418 -
Coils Coil Coil - - 1153 1173 -
SMART SM00260 chew_2 IPR002545 CheW-like domain 1677 1821 1.1E-25

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.