Pseudomonas aeruginosa AZPAE14842, NR60_RS07900

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa AZPAE14842
GCF_000789625.1|latest
Locus Tag
NR60_RS07900
Name
Replicon contig_11
Genomic location 144106 - 146046 (+ strand)

Cross-References

RefSeq WP_003095996.1
GI 489186582
INSDC BAP24930.1
NCBI Locus Tag NR60_RS07900
UniParc UPI0001E9EBF4
UniProtKB Acc A0A077K5S7
UniProtKB ID A0A077K5S7_PSEAI
UniRef100 UniRef100_A0A077K5S7
UniRef50 UniRef50_O33407
UniRef90 UniRef90_O33407

Product

Feature Type CDS
Coding Frame 1
Product Name
esterase
Synonyms
Evidence for Translation
Charge (pH 7) -21.63
Kyte-Doolittle Hydrophobicity Value -0.374
Molecular Weight (kDa) 69.6
Isoelectric Point (pI) 4.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3KVN HYDROLASE 11/30/09 Crystal structure of the full-length autotransporter EstA from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.499 X-RAY DIFFRACTION 99.8

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
(Hydroxyethyloxy)Tri(Ethyloxy)Octane DB04233 DrugBank 5.1.4 O33407 Esterase EstA 99.8 646 0.0e+00

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004538 (814 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: NR60_RS07900
Search term: esterase

Human Homologs

References

No references are associated with this feature.