Pseudomonas aeruginosa AZPAE14847, NR65_RS08140

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 290 371 1.04E-18
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 542 645 1.46E-6
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 487 505 1.3E-17
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 452 466 1.3E-17
Gene3D G3DSA:3.40.50.2300 - - - 661 785 1.4E-48
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 306 370 7.6E-18
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 470 480 1.3E-17
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 416 527 8.2E-40
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 416 526 4.3E-28
CDD cd16922 HATPase_EvgS-ArcB-TorS-like - - 421 525 3.10718E-52
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 359 528 2.36E-48
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 663 776 4.5E-41
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 305 370 2.2E-22
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 665 776 6.88539E-54
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 304 366 4.70212E-10
FunFam G3DSA:3.30.565.10:FF:000078 Two-component sensor histidine kinase - - 369 528 2.8E-59
FunFam G3DSA:3.40.50.2300:FF:000510 Probable sensor/response regulator hybrid - - 657 780 6.6E-61
Coils Coil Coil - - 246 298 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 511 524 1.3E-17
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 665 776 3.7E-27
Gene3D G3DSA:1.10.287.130 - - - 270 368 1.6E-25
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 662 781 3.98E-42
FunFam G3DSA:1.10.287.130:FF:000004 Ethylene receptor 1 - - 272 368 2.7E-30
PANTHER PTHR45339 HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J - - 246 782 0.0
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 369 527 2.8E-49

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.