Pseudomonas aeruginosa 2192, PA2G_01223

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_01223
Name
Replicon	chromosome
Genomic location	1337774 - 1340296 (+ strand)

Cross-References

RefSeq	ZP_04933888.1
GI	254240566
NCBI Locus Tag	PA2G_01223
UniProtKB Acc	A3LBF0
UniProtKB ID	A3LBF0_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	ATP-dependent DNA ligase
Synonyms
Evidence for Translation
Charge (pH 7)	18.73
Kyte-Doolittle Hydrophobicity Value	-0.533
Molecular Weight (kDa)	94.0
Isoelectric Point (pI)	9.72

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3N9D	LIGASE	05/28/10	Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain	Pseudomonas aeruginosa	2.3	X-RAY DIFFRACTION	99.4
2FAR	Hydrolase/Transferase	12/07/05	Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese	Pseudomonas aeruginosa	1.9	X-RAY DIFFRACTION	99.0
3N9B	LIGASE	05/28/10	Crystal Structure of the P. aeruginosa LigD phosphoesterase domain	Pseudomonas aeruginosa	1.92	X-RAY DIFFRACTION	99.4
2LJ6	DNA BINDING PROTEIN	09/06/11	Solution Structure and DNA-binding Properties of the Phosphoesterase Domain of DNA Ligase D	Pseudomonas aeruginosa	NOT	SOLUTION NMR	99.4
2FAO	HYDROLASE/TRANSFERASE	12/07/05	Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain	Pseudomonas aeruginosa	1.5	X-RAY DIFFRACTION	99.0
2FAQ	HYDROLASE/TRANSFERASE	12/07/05	Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with ATP and Manganese	Pseudomonas aeruginosa	1.9	X-RAY DIFFRACTION	99.0

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003336 (490 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_01223 Search term: ATP-dependent DNA ligase

Human Homologs

References