Pseudomonas aeruginosa AZPAE14891, NS08_RS11845

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa AZPAE14891
GCF_000790865.1|latest
Locus Tag
NS08_RS11845
Name
Replicon contig_10
Genomic location 76834 - 78267 (- strand)

Cross-References

RefSeq WP_003112388.1
GI 489203290
NCBI Locus Tag NS08_RS11845

Product

Feature Type CDS
Coding Frame 1
Product Name
multidrug transporter MatE
Synonyms
Evidence for Translation
Charge (pH 7) 12.55
Kyte-Doolittle Hydrophobicity Value 0.632
Molecular Weight (kDa) 50.8
Isoelectric Point (pI) 9.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
PmpM PmpM is a multidrug efflux pump belonging to the MATE family of Pseudomonas aeruginosa. PmpM is an H+ drug antiporter and is the first reported case of an H+ coupled efflux pump in the MATE family. PmpM confers resistance to fluoroquinolones, fradiomycin, benzalkonium chloride, chlorhexidine gluconate, ethidium bromide, tetraphenylphosphonium chloride (TPPCl), and rhodamine 6G. [PMID:14679249] ARO:3004077 protein homolog model Perfect 927.2 100.0 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001295 (965 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: NS08_RS11845

Human Homologs

References

No references are associated with this feature.