Pseudomonas denitrificans ATCC 13867, H681_15305 (ligA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00278
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003911 DNA ligase (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03120
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdr03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdr03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdr03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdr03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd17748 BRCT_DNA_ligase_like - - 719 789 9.04866E-25
Gene3D G3DSA:1.10.150.20 - - - 530 612 4.4E-22
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 537 556 180.0
FunFam G3DSA:1.10.150.20:FF:000006 DNA ligase - - 531 610 1.7E-23
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 330 403 3.7E-33
Pfam PF00533 BRCA1 C Terminus (BRCT) domain IPR001357 BRCT domain 716 789 1.2E-9
Coils Coil Coil - - 38 58 -
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 68 328 3.9E-99
SMART SM00292 BRCT_7 IPR001357 BRCT domain 716 793 1.5E-8
Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type 420 459 9.8E-12
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 331 413 3.08E-28
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 664 683 540.0
NCBIfam TIGR00575 JCVI: DNA ligase (NAD(+)) LigA IPR001679 NAD-dependent DNA ligase 14 616 0.0
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 4 329 4.86E-118
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 617 795 1.0E-30
FunFam G3DSA:1.10.150.20:FF:000007 DNA ligase - - 455 530 1.0E-29
SMART SM00532 ligaN3 IPR013840 NAD-dependent DNA ligase, N-terminal 6 473 0.0
Pfam PF03120 NAD-dependent DNA ligase OB-fold domain IPR004150 NAD-dependent DNA ligase, OB-fold 335 411 7.9E-35
PIRSF PIRSF001604 LigA IPR001679 NAD-dependent DNA ligase 1 625 0.0
SUPERFAMILY SSF52113 BRCT domain IPR036420 BRCT domain superfamily 717 790 2.62E-17
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 417 603 4.08E-51
Gene3D G3DSA:1.10.150.20 - - - 625 706 3.1E-7
Gene3D G3DSA:6.20.10.30 - - - 404 454 1.4E-13
FunFam G3DSA:3.30.470.30:FF:000001 DNA ligase - - 68 328 4.2E-107
PANTHER PTHR23389 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 - - 16 768 6.8E-52
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 471 490 41.0
Pfam PF01653 NAD-dependent DNA ligase adenylation domain IPR013839 NAD-dependent DNA ligase, adenylation 7 331 5.4E-127
Hamap MF_01588 DNA ligase [ligA]. IPR001679 NAD-dependent DNA ligase 5 790 52.667305
SUPERFAMILY SSF47781 RuvA domain 2-like IPR010994 RuvA domain 2-like 620 707 7.04E-7
CDD cd00114 LIGANc IPR013839 NAD-dependent DNA ligase, adenylation 9 330 0.0
FunFam G3DSA:1.10.287.610:FF:000002 DNA ligase - - 2 67 3.9E-30
Gene3D G3DSA:3.40.50.10190 BRCT domain IPR036420 BRCT domain superfamily 707 792 2.3E-23
FunFam G3DSA:2.40.50.140:FF:000012 DNA ligase - - 330 403 5.1E-35
Pfam PF12826 Helix-hairpin-helix motif IPR041663 DisA/LigA, helix-hairpin-helix motif 535 598 6.0E-20
Gene3D G3DSA:1.10.287.610 Helix hairpin bin - - 1 67 4.3E-29
SMART SM00278 HhH1_4 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 505 524 330.0
Gene3D G3DSA:1.10.150.20 - - - 455 529 7.3E-28

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.