Pseudomonas protegens CHA0, PFLCHA0_c54260 (proA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.605.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004350 glutamate-5-semialdehyde dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00412
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc L-proline biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pprc01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-<i>N<sup>&delta;</sup></i>-acetylornithine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pprc01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc00332 Carbapenem biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pprc01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. IPR000965 GPR domain 28 440 42.162144
NCBIfam TIGR00407 JCVI: glutamate-5-semialdehyde dehydrogenase IPR000965 GPR domain 36 430 0.0
CDD cd07079 ALDH_F18-19_ProA-GPR IPR000965 GPR domain 30 436 0.0
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 35 437 0.0
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 33 302 2.8E-15
MobiDBLite mobidb-lite consensus disorder prediction - - 1 21 -
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 333 397 7.5E-7
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 28 440 4.19E-121
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 249 398 0.0
FunFam G3DSA:3.40.309.10:FF:000006 Gamma-glutamyl phosphate reductase - - 249 398 4.2E-59
PANTHER PTHR11063 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE - - 21 440 0.0
PIRSF PIRSF000151 GPR IPR012134 Glutamate-5-semialdehyde dehydrogenase 21 441 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.