Pseudomonas protegens Pf-5, PFL_5227 (panB_1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015940 pantothenate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR20881
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR20881
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfl01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc phosphopantothenate biosynthesis III (archaebacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfl00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR20881 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE IPR003700 Ketopantoate hydroxymethyltransferase 5 273 1.1E-82
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 10 269 1.15E-90
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 1 269 6.4E-93
CDD cd06557 KPHMT-like IPR003700 Ketopantoate hydroxymethyltransferase 12 263 0.0
Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. IPR003700 Ketopantoate hydroxymethyltransferase 10 269 37.6483
Pfam PF02548 Ketopantoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 10 264 5.5E-96
PIRSF PIRSF000388 PanB IPR003700 Ketopantoate hydroxymethyltransferase 1 272 3.9E-96
NCBIfam TIGR00222 JCVI: 3-methyl-2-oxobutanoate hydroxymethyltransferase IPR003700 Ketopantoate hydroxymethyltransferase 14 269 1.4E-83

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.