Pseudomonas sp. UW4, PputUW4_04783 (mrdA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppuu00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG ppuu01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 250 622 2.3E-103
PANTHER PTHR30627 PEPTIDOGLYCAN D,D-TRANSPEPTIDASE - - 11 611 0.0
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 251 607 3.27E-102
Pfam PF03717 Penicillin-binding Protein dimerisation domain IPR005311 Penicillin-binding protein, dimerisation domain 64 236 1.7E-42
Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. IPR017790 Penicillin-binding protein 2 3 611 52.409584
Gene3D G3DSA:3.30.1390.30 - - - 85 161 3.1E-49
NCBIfam TIGR03423 JCVI: penicillin-binding protein 2 IPR017790 Penicillin-binding protein 2 20 607 0.0
SUPERFAMILY SSF56519 Penicillin binding protein dimerisation domain IPR036138 Penicillin-binding protein, dimerisation domain superfamily 56 250 5.49E-51
Gene3D G3DSA:3.90.1310.10 - - - 64 246 3.1E-49
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 268 604 6.8E-77

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.