Pseudomonas sp. UW4, PputUW4_02396

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.15.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type 88 288 9.8E-33
SUPERFAMILY SSF55869 DNA topoisomerase I domain IPR035447 DNA topoisomerase I, N-terminal domain superfamily 28 89 1.83E-21
Gene3D G3DSA:3.90.15.10 Topoisomerase I; Chain A, domain 3 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type 119 238 2.8E-88
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 237 251 1.5E-8
Gene3D G3DSA:1.10.132.120 - - - 96 323 2.8E-88
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 128 147 1.5E-8
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 172 188 1.5E-8
SUPERFAMILY SSF56349 DNA breaking-rejoining enzymes IPR011010 DNA breaking-rejoining enzyme, catalytic core 84 319 2.94E-73
PRINTS PR00416 Eukaryotic DNA topoisomerase I signature IPR001631 DNA topoisomerase I 151 165 1.5E-8
Gene3D G3DSA:3.30.66.10 DNA topoisomerase I domain IPR035447 DNA topoisomerase I, N-terminal domain superfamily 11 94 2.7E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.