Pseudomonas savastanoi pv. phaseolicola 1448A, PSPPH_4399 (lipA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009107 lipoate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00206
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016992 lipoate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00206
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00206
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psp00785 Lipoic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00729 MiaB IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain 97 306 1.6E-13
SFLD SFLDF00271 lipoyl synthase IPR003698 Lipoyl synthase 49 329 0.0
SFLD SFLDG01058 lipoyl synthase like - - 49 329 0.0
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 104 263 2.7E-13
FunFam G3DSA:3.20.20.70:FF:000023 Lipoyl synthase - - 94 305 6.3E-119
SUPERFAMILY SSF102114 Radical SAM enzymes - - 63 330 1.18E-66
CDD cd01335 Radical_SAM - - 104 279 8.72131E-6
PIRSF PIRSF005963 Lipoyl_synth IPR003698 Lipoyl synthase 11 334 7.1E-129
NCBIfam TIGR00510 JCVI: lipoyl synthase IPR003698 Lipoyl synthase 47 327 1.8E-127
Hamap MF_00206 Lipoyl synthase [lipA]. IPR003698 Lipoyl synthase 49 335 153.103088
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 94 309 1.1E-18
PANTHER PTHR10949 LIPOYL SYNTHASE IPR003698 Lipoyl synthase 48 328 4.8E-114
Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family IPR031691 Lipoyl synthase, N-terminal 51 86 3.0E-7

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.