Pseudomonas mendocina NK-01, MDS_4600

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008460 dTDP-glucose 4,6-dehydratase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01181
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009225 nucleotide-sugar metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01181
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pmk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-L-megosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-daunosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-&beta;-L-4-<i>epi</i>-vancosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-olivose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-6-deoxy-&alpha;-D-allose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-<i>N</i>-acetylviosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-&alpha;-D-mycaminose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-&beta;-L-digitoxose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-forosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-&beta;-fucofuranose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-3-acetamido-3,6-dideoxy-&alpha;-D-glucose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-<i>N</i>-acetylthomosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-3-acetamido-&alpha;-D-fucose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk00525 Acarbose and validamycin biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-4-<i>O</i>-demethyl-&beta;-L-noviose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-mycarose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-D-desosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk00521 Streptomycin biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00523 Polyketide sugar unit biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR01181 JCVI: dTDP-glucose 4,6-dehydratase IPR005888 dTDP-glucose 4,6-dehydratase 2 339 0.0
Gene3D G3DSA:3.90.25.10 - - - 200 333 0.0
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 337 1.61E-95
Pfam PF16363 GDP-mannose 4,6 dehydratase IPR016040 NAD(P)-binding domain 4 326 1.5E-98
Gene3D G3DSA:3.40.50.720 - - - 2 324 0.0
PANTHER PTHR43000 DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED - - 2 341 1.6E-118
CDD cd05246 dTDP_GD_SDR_e IPR005888 dTDP-glucose 4,6-dehydratase 1 333 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.