Pseudomonas mendocina NK-01, MDS_3431

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides biosynthesis from CTP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 371 906 0.0
FunFam G3DSA:3.20.70.20:FF:000009 Ribonucleoside-diphosphate reductase - - 218 915 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 618 641 8.9E-48
NCBIfam TIGR02506 JCVI: ribonucleoside-diphosphate reductase subunit alpha IPR013346 Ribonucleotide reductase, class I, alpha subunit, C-terminal 296 907 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 446 465 8.9E-48
SUPERFAMILY SSF48168 R1 subunit of ribonucleotide reductase, N-terminal domain IPR008926 Ribonucleotide reductase R1 subunit, N-terminal 154 369 8.37E-64
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 581 592 8.9E-48
PANTHER PTHR11573 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN IPR039718 Ribonucleoside-diphosphate reductase large subunit 149 968 0.0
Pfam PF00317 Ribonucleotide reductase, all-alpha domain IPR013509 Ribonucleotide reductase large subunit, N-terminal 293 365 1.3E-22
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 33 127 7.1E-18
Gene3D G3DSA:3.20.70.20 - - - 218 915 0.0
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 370 907 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 760 787 8.9E-48
MobiDBLite mobidb-lite consensus disorder prediction - - 1 23 -
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 656 678 8.9E-48
CDD cd01679 RNR_I - - 318 907 0.0
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 149 232 1.1E-7
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 684 707 8.9E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.