Pseudomonas aeruginosa 2192, PA2G_00140

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa 2192
GCF_000152545.1|latest
Locus Tag
PA2G_00140
Name
Replicon chromosome
Genomic location 142345 - 145236 (- strand)

Cross-References

RefSeq ZP_04932848.1
GI 254239526
NCBI Locus Tag PA2G_00140
UniProtKB Acc A3L5Y7
UniProtKB ID A3L5Y7_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
ribonucleotide-diphosphate reductase subunit alpha
Synonyms
Evidence for Translation
Charge (pH 7) -14.68
Kyte-Doolittle Hydrophobicity Value -0.314
Molecular Weight (kDa) 107.2
Isoelectric Point (pI) 5.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5IM3 OXIDOREDUCTASE 03/05/16 Crystal structure of the class I ribonucleotide reductase from Pseudomonas aeruginosa in complex with dATP Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) 2.298 X-RAY DIFFRACTION 99.8

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001115 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2G_00140

Human Homologs

Ensembl 110, assembly GRCh38.p14
ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451]
E-value: 1.1e-156
Percent Identity: 40.9

References

No references are associated with this feature.