Pseudomonas aeruginosa AZPAE14395, NQ58_RS14720

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00260
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00260
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00088
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 951 1.4E-13
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2084 2098 1.5E-10
Coils Coil Coil - - 1368 1388 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1675 1768 3.9E-15
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2357 2469 1.6E-27
Coils Coil Coil - - 232 252 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1360 1490 2.0E-29
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2185 2324 1.2E-22
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1033 1168 5.3E-18
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 862 959 3.5E-6
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1855 1994 1.3E-11
CDD cd16916 HATPase_CheA-like - - 2002 2177 1.15619E-83
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1039 1162 2.88E-19
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 862 987 6.02E-27
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 2260 2320 2.9E-19
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1674 1778 5.48943E-13
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2140 2158 1.5E-10
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1667 1800 3.3E-23
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1624 3.93445E-15
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1360 1458 3.43303E-15
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1528 1627 3.8E-14
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1996 2177 7.99E-36
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1526 1648 1.28E-26
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 2354 2473 3.98E-36
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1526 1655 7.3E-27
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 433 556 1.94E-14
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 2039 2180 1.3E-22
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 2357 2468 3.26562E-30
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1397 1668 0.0
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1673 1770 6.4E-4
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1360 1457 6.6E-7
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1182 1302 1.53E-13
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1995 2179 1.7E-60
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 2179 2318 1.7E-21
MobiDBLite mobidb-lite consensus disorder prediction - - 594 613 -
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1993 2179 1.0E-52
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 862 958 4.31101E-10
Coils Coil Coil - - 1893 1913 -
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2043 2179 1.8E-16
MobiDBLite mobidb-lite consensus disorder prediction - - 985 1033 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1360 1482 7.07E-28
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1039 1134 0.51
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1127 3.8E-11
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 2355 2468 2.9E-37
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 137 1.3E-11
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2164 2177 1.5E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1674 1782 4.19E-20
Coils Coil Coil - - 1756 1783 -
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1455 5.0E-14
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.0E-8
SMART SM00260 chew_2 IPR002545 CheW-like domain 2172 2322 2.0E-34
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1183 1310 1.4E-12
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1039 1130 2.06848E-5
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1526 1623 0.011
Gene3D G3DSA:3.40.50.2300 - - - 2357 2476 5.3E-40
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 862 992 7.1E-28
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.96E-23
MobiDBLite mobidb-lite consensus disorder prediction - - 565 589 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.