Pseudomonas aeruginosa RP73, M062_20135 (hscA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016226 iron-sulfur cluster assembly
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051082 unfolded protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140662 ATP-dependent protein folding chaperone
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR19375
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006457 protein folding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00679
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Chaperones & heat shock proteins Other RP73 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF100920 Heat shock protein 70kD (HSP70), peptide-binding domain IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily 384 535 2.75E-50
PRINTS PR00301 70kDa heat shock protein signature - - 360 380 2.4E-56
Gene3D G3DSA:3.90.640.10 Actin; Chain A, domain 4 - - 238 311 1.4E-121
PRINTS PR00301 70kDa heat shock protein signature - - 48 60 2.4E-56
Hamap MF_00679 Chaperone protein HscA [hscA]. IPR010236 ISC system FeS cluster assembly, HscA chaperone 1 617 45.431549
SUPERFAMILY SSF53067 Actin-like ATPase domain IPR043129 ATPase, nucleotide binding domain 19 197 1.72E-51
SUPERFAMILY SSF53067 Actin-like ATPase domain IPR043129 ATPase, nucleotide binding domain 200 376 1.5E-47
PRINTS PR00301 70kDa heat shock protein signature - - 466 482 2.4E-56
Gene3D G3DSA:3.30.420.40 - - - 22 374 1.4E-121
NCBIfam TIGR01991 JCVI: Fe-S protein assembly chaperone HscA IPR010236 ISC system FeS cluster assembly, HscA chaperone 21 616 0.0
Coils Coil Coil - - 526 546 -
Gene3D G3DSA:1.20.1270.10 - IPR029048 Heat shock protein 70kD, C-terminal domain superfamily 520 616 2.7E-28
FunFam G3DSA:3.30.420.40:FF:000046 Chaperone protein HscA - - 22 205 4.4E-64
PRINTS PR00301 70kDa heat shock protein signature - - 20 33 2.4E-56
PRINTS PR00301 70kDa heat shock protein signature - - 329 345 2.4E-56
PANTHER PTHR19375 HEAT SHOCK PROTEIN 70KDA IPR013126 Heat shock protein 70 family 21 548 3.0E-128
SUPERFAMILY SSF100934 Heat shock protein 70kD (HSP70), C-terminal subdomain IPR029048 Heat shock protein 70kD, C-terminal domain superfamily 504 615 2.75E-33
PRINTS PR00301 70kDa heat shock protein signature - - 211 221 2.4E-56
CDD cd10236 HscA_like_NBD IPR042039 HscA chaperone, nucleotide-binding domain 20 375 0.0
FunFam G3DSA:2.60.34.10:FF:000005 Chaperone protein HscA homolog - - 380 519 2.1E-80
Gene3D G3DSA:3.30.420.40 - - - 194 361 1.4E-121
Pfam PF00012 Hsp70 protein IPR013126 Heat shock protein 70 family 21 600 0.0
PRINTS PR00301 70kDa heat shock protein signature - - 152 172 2.4E-56
Gene3D G3DSA:2.60.34.10 Substrate Binding Domain Of DNAk; Chain A, domain 1 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily 379 517 1.0E-48
PRINTS PR00301 70kDa heat shock protein signature - - 385 404 2.4E-56

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.