Pseudomonas aeruginosa RP73, M062_13990

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2634
 ECO:0000249
sequence similarity evidence used in automatic assertion		 23363478
Molecular Function GO:0004451 isocitrate lyase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA2634
 ECO:0000249
sequence similarity evidence used in automatic assertion		 17319879
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51621
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019752 carboxylic acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR21631
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004451 isocitrate lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR21631
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 412 531 5.9E-8
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 1 278 7.0E-29
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 429 530 2.8E-13
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 330 399 1.3E-9
SUPERFAMILY SSF51621 Phosphoenolpyruvate/pyruvate domain IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 10 514 2.42E-124
PIRSF PIRSF001362 ICL IPR006254 Isocitrate lyase 290 410 7.7E-12
PANTHER PTHR21631 ISOCITRATE LYASE/MALATE SYNTHASE IPR006254 Isocitrate lyase 2 531 2.7E-130
Gene3D G3DSA:3.20.20.60 - IPR040442 Pyruvate kinase-like domain superfamily 2 531 1.0E-128
CDD cd00377 ICL_PEPM IPR039556 ICL/PEPM domain 63 386 2.08677E-34
Pfam PF00463 Isocitrate lyase family IPR006254 Isocitrate lyase 81 269 3.5E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.