Pseudomonas aeruginosa AZPAE14443, NQ69_RS17375

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1991 2175 1.7E-60
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1185 1312 8.6E-14
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.83E-23
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1759 2471 0.0
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1669 1766 6.4E-4
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1043 1129 2.5E-11
MobiDBLite mobidb-lite consensus disorder prediction - - 658 681 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1522 1644 1.83E-26
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 137 1.3E-11
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1524 1623 4.7E-14
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 2175 2314 1.7E-21
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 864 989 5.63E-27
MobiDBLite mobidb-lite consensus disorder prediction - - 565 618 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2136 2154 1.5E-10
CDD cd16916 HATPase_CheA-like - - 1998 2173 1.22325E-83
Coils Coil Coil - - 232 252 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 960 3.94239E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 3.0E-8
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1184 1304 1.91E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2080 2094 1.5E-10
Coils Coil Coil - - 1889 1909 -
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 2035 2176 1.3E-22
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1035 1170 3.3E-18
Gene3D G3DSA:3.40.50.2300 - - - 2353 2472 5.3E-40
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2181 2320 1.2E-22
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1459 6.6E-7
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1132 2.0055E-5
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1992 2173 7.99E-36
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 866 953 1.6E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1670 1778 4.19E-20
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 2350 2469 3.98E-36
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 2353 2464 3.04606E-30
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2160 2173 1.5E-10
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1666 1802 2.9E-23
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1619 0.0095
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 433 556 1.94E-14
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1362 1484 1.83E-27
SMART SM00260 chew_2 IPR002545 CheW-like domain 2168 2318 2.0E-34
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1041 1164 4.84E-19
MobiDBLite mobidb-lite consensus disorder prediction - - 987 1035 -
Coils Coil Coil - - 1752 1779 -
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2353 2465 1.6E-27
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 2351 2464 2.9E-37
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1362 1460 3.20155E-15
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 864 994 4.5E-28
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1364 1457 6.7E-14
Coils Coil Coil - - 1370 1390 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1362 1492 5.1E-29
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1671 1764 3.9E-15
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1522 1620 5.41666E-15
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1522 1651 3.6E-27
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 2256 2316 2.9E-19
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 864 961 3.8E-6
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1670 1774 5.16924E-13
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2039 2175 1.8E-16
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1851 1990 1.3E-11
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1989 2175 1.0E-52
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1041 1144 0.49

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.