Pseudomonas aeruginosa B136-33, G655_25940 (nadE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR23090
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR23090
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008795 NAD+ synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00193
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004359 glutaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR23090
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR23090
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other B136-33 genes in this class
Amino acid biosynthesis and metabolism Other B136-33 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psg01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg00760 Nicotinate and nicotinamide metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02540 NAD synthase IPR022310 NAD/GMP synthase 28 272 9.0E-65
PANTHER PTHR23090 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE IPR003694 NAD(+) synthetase 23 254 6.3E-37
NCBIfam TIGR00552 JCVI: NAD(+) synthase IPR003694 NAD(+) synthetase 27 273 3.6E-67
Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. IPR022926 NH(3)-dependent NAD(+) synthetase 23 275 50.742916
CDD cd00553 NAD_synthase IPR003694 NAD(+) synthetase 23 269 7.56414E-88
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 1 275 2.6E-95
FunFam G3DSA:3.40.50.620:FF:000253 NH(3)-dependent NAD(+) synthetase - - 1 275 0.0
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 20 272 3.45E-77

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.