Pseudomonas aeruginosa B136-33, G655_20990 (phhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005506 iron ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11473
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00372
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004505 phenylalanine 4-monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009072 aromatic amino acid family metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11473
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004497 monooxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11473
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006559 L-phenylalanine catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd03348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other B136-33 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psg01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg00360 Phenylalanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 209 228 1.9E-9
Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase IPR019774 Aromatic amino acid hydroxylase, C-terminal 16 229 1.4E-47
CDD cd03348 pro_PheOH IPR005960 Phenylalanine-4-hydroxylase, monomeric form 9 233 8.94922E-127
SUPERFAMILY SSF56534 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily 3 248 4.58E-101
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 138 157 1.9E-9
Gene3D G3DSA:1.10.800.10 Aromatic amino acid hydroxylase IPR036951 Aromatic amino acid hydroxylase superfamily 1 262 5.9E-99
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 74 96 1.9E-9
NCBIfam TIGR01267 JCVI: phenylalanine 4-monooxygenase IPR005960 Phenylalanine-4-hydroxylase, monomeric form 9 254 0.0
PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature IPR019774 Aromatic amino acid hydroxylase, C-terminal 178 196 1.9E-9
PANTHER PTHR11473 AROMATIC AMINO ACID HYDROXYLASE IPR001273 Aromatic amino acid hydroxylase 12 232 4.8E-71

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.