Pseudomonas aeruginosa B136-33, G655_09955 (fabG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006633 fatty acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other B136-33 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psg00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01212 Fatty acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg00061 Fatty acid biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01040 Biosynthesis of unsaturated fatty acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psg01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 4 246 6.59E-83
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 154 173 3.3E-12
FunFam G3DSA:3.40.50.720:FF:000037 3-oxoacyl-[acyl-carrier-protein] reductase FabG - - 1 247 1.1E-127
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 81 92 3.3E-12
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 208 228 3.6E-46
PANTHER PTHR42879 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE - - 1 245 5.1E-85
SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. - - 6 185 1.3E-5
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 128 144 3.6E-46
CDD cd05333 BKR_SDR_c - - 6 245 7.55475E-125
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 134 142 3.3E-12
NCBIfam TIGR01830 JCVI: 3-oxoacyl-[acyl-carrier-protein] reductase IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase 8 245 3.9E-100
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 81 92 3.6E-46
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 7 24 3.6E-46
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 154 173 3.6E-46
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 175 192 3.6E-46
Gene3D G3DSA:3.40.50.720 - - - 1 247 4.8E-87
Pfam PF13561 Enoyl-(Acyl carrier protein) reductase - - 12 244 2.9E-63

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.