Pseudomonas aeruginosa DK2, PADK2_29445

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006221 pyrimidine nucleotide biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5541
 ECO:0000249
sequence similarity evidence used in automatic assertion		 15278241
Molecular Function GO:0004151 dihydroorotase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5541
 ECO:0000249
sequence similarity evidence used in automatic assertion		 15278241
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01979
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.40.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51338 Composite domain of metallo-dependent hydrolases IPR011059 Metal-dependent hydrolase, composite domain superfamily 1 432 7.34E-25
SUPERFAMILY SSF51556 Metallo-dependent hydrolases IPR032466 Metal-dependent hydrolase 55 371 3.06E-91
CDD cd01318 DHOase_IIb - - 49 423 0.0
Pfam PF01979 Amidohydrolase family IPR006680 Amidohydrolase-related 231 425 6.8E-6
Gene3D G3DSA:3.20.20.140 - - - 56 412 2.6E-127
PANTHER PTHR43668 ALLANTOINASE - - 2 431 6.1E-83
Gene3D G3DSA:2.30.40.10 Urease, subunit C, domain 1 IPR011059 Metal-dependent hydrolase, composite domain superfamily 6 428 2.6E-127

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.