Pseudomonas aeruginosa DK2, PADK2_25260

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0071230 cellular response to amino acid stimulus
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4758
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8169201
Molecular Function GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006541 glutamine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other DK2 genes in this class
Nucleotide biosynthesis and metabolism Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdk00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 233 247 5.3E-39
PANTHER PTHR11405 CARBAMOYLTRANSFERASE FAMILY MEMBER - - 3 360 4.0E-53
PRINTS PR00097 Anthranilate synthase component II signature - - 349 362 1.1E-5
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 306 317 5.3E-39
FunFam G3DSA:3.50.30.20:FF:000001 Carbamoyl-phosphate synthase small chain - - 2 151 8.8E-66
SUPERFAMILY SSF52021 Carbamoyl phosphate synthetase, small subunit N-terminal domain IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily 4 144 1.96E-56
Gene3D G3DSA:3.50.30.20 - IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily 2 151 1.9E-63
Pfam PF00117 Glutamine amidotransferase class-I IPR017926 Glutamine amidotransferase 197 372 1.8E-46
PRINTS PR00097 Anthranilate synthase component II signature - - 264 275 1.1E-5
Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. IPR006274 Carbamoyl-phosphate synthase, small subunit 3 378 47.7276
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 194 208 5.3E-39
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 153 377 3.21E-62
CDD cd01744 GATase1_CPSase IPR035686 Carbamoyl-phosphate synthase small subunit, GATase1 domain 194 371 1.93367E-111
PRINTS PR00097 Anthranilate synthase component II signature - - 236 245 1.1E-5
Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain 7 132 2.4E-50
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 264 275 3.1E-11
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 349 362 3.1E-11
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 152 377 2.7E-81
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 264 280 5.3E-39
NCBIfam TIGR01368 JCVI: glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit IPR006274 Carbamoyl-phosphate synthase, small subunit 5 375 0.0
SMART SM01097 CPSase_sm_chain_2 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain 3 133 8.9E-92
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 236 245 3.1E-11
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature - - 281 298 5.3E-39
FunFam G3DSA:3.40.50.880:FF:000011 Carbamoyl-phosphate synthase small chain - - 152 378 2.9E-130

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.