Pseudomonas aeruginosa DK2, PADK2_18965

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02954
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other DK2 genes in this class
Transcriptional regulators Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 398 438 2.5E-8
CDD cd17549 REC_DctD-like - - 7 136 1.4972E-69
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 358 440 5.82E-10
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 7 115 4.7E-27
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 5 116 2.5E-31
Gene3D G3DSA:1.10.8.60 - - - 317 388 3.0E-21
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 166 328 6.1E-8
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 146 312 4.7E-66
CDD cd00009 AAA - - 147 310 4.03482E-25
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 139 316 1.4E-71
Gene3D G3DSA:1.10.10.60 - - - 392 441 6.3E-13
FunFam G3DSA:3.40.50.2300:FF:000018 DNA-binding transcriptional regulator NtrC - - 4 134 8.0E-41
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 404 421 4.4E-7
Gene3D G3DSA:3.40.50.2300 - - - 6 145 8.1E-35
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 146 375 4.83E-67
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 146 316 2.9E-61
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 3 191 5.83E-44
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 5 441 0.0
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 421 441 4.4E-7

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.