Pseudomonas aeruginosa DK2, PADK2_12600

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other DK2 genes in this class
Antibiotic resistance and susceptibility Other DK2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdk02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR01730 JCVI: efflux RND transporter periplasmic adaptor subunit IPR006143 RND efflux pump, membrane fusion protein 64 392 1.4E-80
Gene3D G3DSA:2.40.50.100 - - - 88 232 2.2E-70
Gene3D G3DSA:2.40.420.20 - - - 302 393 1.1E-25
FunFam G3DSA:2.40.30.170:FF:000006 Multidrug resistance protein MdtA - - 228 301 2.2E-27
Coils Coil Coil - - 129 156 -
PANTHER PTHR30469 MULTIDRUG RESISTANCE PROTEIN MDTA - - 12 396 2.0E-107
FunFam G3DSA:2.40.420.20:FF:000001 Efflux RND transporter periplasmic adaptor subunit - - 302 393 2.8E-26
Gene3D G3DSA:2.40.30.170 - - - 82 301 2.2E-70
MobiDBLite mobidb-lite consensus disorder prediction - - 409 426 -
MobiDBLite mobidb-lite consensus disorder prediction - - 394 426 -
SUPERFAMILY SSF111369 HlyD-like secretion proteins - - 78 315 1.57E-60
Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain 87 311 5.8E-14
Gene3D G3DSA:1.10.287.470 Helix hairpin bin - - 123 196 2.2E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.