Pseudomonas aeruginosa M18, PAM18_4833 (cbrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000160 phosphorelay signal transduction system
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 11401699
Biological Process GO:2000147 positive regulation of cell motility
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 21169488
Biological Process GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 21169488
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other M18 genes in this class
Carbon compound catabolism Other M18 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd10322 SLC5sbd - - 11 491 6.94473E-55
Gene3D G3DSA:3.30.450.20 PAS domain - - 624 750 3.7E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 933 951 2.7E-15
SMART SM00091 pas_2 IPR000014 PAS domain 632 700 3.2E-4
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 623 716 5.33E-9
MobiDBLite mobidb-lite consensus disorder prediction - - 958 983 -
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 633 748 2.0E-8
PANTHER PTHR43065 SENSOR HISTIDINE KINASE - - 543 980 1.8E-70
Gene3D G3DSA:1.20.1730.10 Sodium/glucose cotransporter IPR038377 Sodium/glucose symporter superfamily 35 519 1.7E-44
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 961 974 2.7E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 902 916 2.7E-15
FunFam G3DSA:1.10.287.130:FF:000022 Two-component sensor CbrA - - 748 819 6.8E-47
CDD cd00130 PAS IPR000014 PAS domain 641 738 0.0024115
Pfam PF00989 PAS fold IPR013767 PAS fold 635 718 7.7E-6
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 757 819 1.7E-11
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 865 977 1.2E-36
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 817 978 2.23E-40
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 754 817 1.29099E-11
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 865 975 3.9E-23
Gene3D G3DSA:1.10.287.130 - - - 751 819 1.3E-19
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 750 819 1.79E-10
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 823 977 7.3E-42
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 756 822 1.1E-10
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 920 930 2.7E-15

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.