Pseudomonas aeruginosa M18, PAM18_3752 (cobQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009236 cobalamin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00028
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00028
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 6 240 2.92E-58
CDD cd01750 GATase1_CobQ IPR033949 Cobyric acid synthase, glutamine amidotransferase type 1 255 444 4.47546E-75
PANTHER PTHR21343 DETHIOBIOTIN SYNTHETASE - - 6 486 0.0
Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain IPR011698 CobB/CobQ-like glutamine amidotransferase 254 437 6.9E-58
NCBIfam TIGR00313 JCVI: cobyric acid synthase CobQ IPR004459 Cobyric acid synthase CobQ 8 478 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 3 244 5.6E-62
Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain 8 233 4.1E-23
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 257 401 7.5E-16
Hamap MF_00028 Cobyric acid synthase [cobQ]. IPR004459 Cobyric acid synthase CobQ 1 488 216.093628
CDD cd05389 CobQ_N IPR047045 Cobyric acid synthase, N-terminal domain 6 228 0.0
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 254 447 5.77E-42

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.