Pseudomonas aeruginosa M18, PAM18_3566

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other M18 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	paf02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Coils	Coil	Coil	-	-	363	390	-
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	392	460	1.7E-5
SUPERFAMILY	SSF103190	Sensory domain-like	IPR029151	Periplasmic sensor-like domain superfamily	65	189	1.61E-13
Pfam	PF02743	Cache domain	IPR033479	Double Cache domain 1	36	285	4.7E-18
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	394	457	2.7E-6
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	381	458	7.46E-9
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	538	552	5.4E-12
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	593	606	5.4E-12
FunFam	G3DSA:1.10.287.130:FF:000049	C4-dicarboxylate transport sensor protein DctB	-	-	368	455	1.3E-33
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	500	607	2.0E-19
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	569	587	5.4E-12
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	390	456	1.6495E-5
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	463	609	3.54E-31
Gene3D	G3DSA:1.10.287.130	-	-	-	368	454	2.2E-18
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	181	295	2.2E-24
Gene3D	G3DSA:6.10.250.3020	-	-	-	36	98	6.7E-9
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	455	607	1.1E-31
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	101	180	9.6E-29
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	556	566	5.4E-12
PANTHER	PTHR43065	SENSOR HISTIDINE KINASE	-	-	215	611	8.6E-49
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	499	609	1.6E-26
PIRSF	PIRSF036431	HK_DctB	IPR017055	Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator)	1	616	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.