Pseudomonas aeruginosa M18, PAM18_3268 (cobA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01469
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019354 siroheme biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01469
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.1010.10 - IPR014777 Tetrapyrrole methylase, subdomain 1 1 117 6.2E-40
SUPERFAMILY SSF53790 Tetrapyrrole methylase IPR035996 Tetrapyrrole methylase superfamily 1 235 4.58E-71
NCBIfam TIGR01469 JCVI: uroporphyrinogen-III C-methyltransferase IPR006366 Uroporphyrin-III C-methyltransferase 3 234 1.4E-93
Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases IPR000878 Tetrapyrrole methylase 4 212 5.2E-46
FunFam G3DSA:3.30.950.10:FF:000010 Uroporphyrin-III C-methyltransferase - - 118 240 9.6E-67
PANTHER PTHR45790 SIROHEME SYNTHASE-RELATED - - 2 234 5.6E-83
Gene3D G3DSA:3.30.950.10 - IPR014776 Tetrapyrrole methylase, subdomain 2 118 240 2.4E-38
CDD cd11642 SUMT IPR006366 Uroporphyrin-III C-methyltransferase 8 232 1.0049E-118
FunFam G3DSA:3.40.1010.10:FF:000001 Siroheme synthase - - 1 117 5.2E-46

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.