Pseudomonas aeruginosa M18, PAM18_1754 (cyaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004016 adenylate cyclase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3217
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12586068
Biological Process GO:0009405 pathogenesis
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3217
 ECO:0000249
sequence similarity evidence used in automatic assertion		 14977975
Biological Process GO:0006171 cAMP biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3217
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12586068
Biological Process GO:0035556 intracellular signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00211
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009190 cyclic nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00211
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other M18 genes in this class
Adaptation, Protection Other M18 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG paf00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG paf02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 204 393 1.11E-61
Pfam PF05230 MASE2 domain IPR007894 MASE2 2 91 1.1E-29
Coils Coil Coil - - 162 182 -
FunFam G3DSA:3.30.70.1230:FF:000025 Adenylate cyclase 1 - - 202 399 1.4E-127
Gene3D G3DSA:3.30.70.1230 Nucleotide cyclase IPR029787 Nucleotide cyclase 202 399 1.0E-68
SMART SM00044 cyc_6 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase 171 381 2.0E-34
Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase 208 391 1.4E-37
CDD cd07302 CHD IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase 211 391 7.182E-60
PANTHER PTHR43081 ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED - - 131 391 5.2E-43
Coils Coil Coil - - 423 443 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.