Pseudomonas aeruginosa PA7, PSPA7_5576
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_5576
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 5744639 - 5747527 (+ strand) |
Cross-References
| RefSeq | YP_001350897.1 |
| GI | 152989022 |
| Entrez | 5357695 |
| NCBI Locus Tag | PSPA7_5576 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
sensor/response regulator hybrid
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -2.60 |
| Kyte-Doolittle Hydrophobicity Value | 0.100 |
| Molecular Weight (kDa) | 106104.7 |
| Isoelectric Point (pI) | 6.74 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6DK8 | SIGNALING PROTEIN | 05/29/18 | RetS kinase region without cobalt | Pseudomonas aeruginosa | 3.8 | X-RAY DIFFRACTION | 98.3 |
| 2XBZ | TRANSFERASE | 04/15/10 | Multiple oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand-binding site | PSEUDOMONAS AERUGINOSA | 2.65 | X-RAY DIFFRACTION | 97.2 |
| 3JYB | TRANSFERASE | 09/21/09 | Crystal Structure of the RetS periplasmic domain | Pseudomonas aeruginosa | 2.04 | X-RAY DIFFRACTION | 97.2 |
| 6DK7 | SIGNALING PROTEIN | 05/29/18 | RetS histidine kinase region with cobalt | Pseudomonas aeruginosa | 2.6 | X-RAY DIFFRACTION | 98.2 |
| 7N0E | SIGNALING PROTEIN | 05/25/21 | Co-complex of the histidine kinase region of RetS and the dimerization and histidine phosphotransfer domain of GacS | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 98.2 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004485 (533 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_5576
Search term: sensor/response regulator hybrid
|
Human Homologs
References
No references are associated with this feature.