Pseudomonas aeruginosa PA7, PSPA7_5415 (mrcB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008955 peptidoglycan glycosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02071
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02071
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00905
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008233 peptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02071
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009274 peptidoglycan-based cell wall
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02071
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046677 response to antibiotic
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02071
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 432 660 5.6E-18
NCBIfam TIGR02071 JCVI: penicillin-binding protein 1B IPR011813 Penicillin-binding protein 1B 27 753 0.0
Gene3D G3DSA:1.10.3810.10 - IPR036950 Penicillin binding protein transglycosylase domain 159 362 0.0
Gene3D G3DSA:1.20.5.100 - - - 19 55 3.0E-6
FunFam G3DSA:1.10.3810.10:FF:000002 Penicillin-binding protein 1B - - 159 362 6.5E-81
Pfam PF14814 Bifunctional transglycosylase second domain IPR028166 Bifunctional transglycosylase second domain 72 155 1.0E-24
Pfam PF00912 Transglycosylase IPR001264 Glycosyl transferase, family 51 167 337 4.0E-57
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 62 726 0.0
PIRSF PIRSF002799 PBP1b IPR011813 Penicillin-binding protein 1B 2 775 0.0
SUPERFAMILY SSF53955 Lysozyme-like IPR023346 Lysozyme-like domain superfamily 164 361 3.09E-66
FunFam G3DSA:3.40.710.10:FF:000006 Penicillin-binding protein 1B - - 356 726 0.0
PANTHER PTHR32282 BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED - - 8 753 0.0
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 320 755 4.7E-119
Gene3D G3DSA:3.30.2060.10 - - - 70 158 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.