Pseudomonas aeruginosa PA7, PSPA7_5199 (lspA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_5199
Name
lspA
Replicon chromosome
Genomic location 5345233 - 5345742 (- strand)

Cross-References

RefSeq YP_001350531.1
GI 152988587
EC Number 3.4.23.36
Entrez 5356993
INSDC ABR85770.1
NCBI Locus Tag PSPA7_5199
UniParc UPI0000D72BA6
UniProtKB Acc A6VBU6
UniProtKB ID LSPA_PSEA7
UniRef100 UniRef100_A6VBU6
UniRef50 UniRef50_Q02GB8
UniRef90 UniRef90_Q02GB8

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein signal peptidase
Synonyms
Evidence for Translation
Charge (pH 7) 1.70
Kyte-Doolittle Hydrophobicity Value 0.643
Molecular Weight (kDa) 19.0
Isoelectric Point (pI) 8.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5DIR HYDROLASE 09/01/15 membrane protein at 2.8 Angstroms Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228); SYNTHETIC CONSTRUCT 2.8 X-RAY DIFFRACTION 97.6
6FMS HYDROLASE 02/02/18 IMISX-EP of Se-LspA Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT 3 X-RAY DIFFRACTION 97.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 512 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004218 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_5199
Search term: lspA

Human Homologs

References

No references are associated with this feature.