Pseudomonas aeruginosa PA7, PSPA7_4272 (fleR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1900191 negative regulation of single-species biofilm formation
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA1099
 ECO:0000249
sequence similarity evidence used in automatic assertion		 15231779
Biological Process GO:2000155 positive regulation of cilium-dependent cell motility
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA1099
 ECO:0000249
sequence similarity evidence used in automatic assertion		 7591148
Biological Process GO:0045785 positive regulation of cell adhesion
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA1099
 ECO:0000249
sequence similarity evidence used in automatic assertion		 7591148
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01590
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PA7 genes in this class
Transcriptional regulators Other PA7 genes in this class
Motility & Attachment Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.2300:FF:000018 DNA-binding transcriptional regulator NtrC - - 1 129 2.5E-40
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 1 456 4.3E-130
CDD cd00009 AAA - - 131 292 4.00961E-23
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 416 455 2.3E-13
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 132 371 7.55E-70
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 5 114 1.8E-25
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 150 293 8.4E-13
Gene3D G3DSA:1.10.10.60 - - - 396 459 1.2E-9
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 127 301 6.7E-64
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 343 455 1.12E-11
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 125 300 1.2E-74
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 422 439 4.8E-6
Gene3D G3DSA:3.40.50.2300 - - - 2 126 4.0E-33
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 135 296 7.3E-67
Gene3D G3DSA:1.10.8.60 - - - 302 376 5.6E-22
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 3 114 1.1E-33
PRINTS PR01590 FIS bacterial regulatory protein HTH signature IPR002197 DNA binding HTH domain, Fis-type 439 459 4.8E-6
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 4 174 9.68E-42

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.