Pseudomonas aeruginosa PA7, PSPA7_4010 (pdxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008615 pyridoxine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd12158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0033711 4-phosphoerythronate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd12158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd12158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046983 protein dimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF11890
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PA7 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PA7 genes in this class
Amino acid biosynthesis and metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00750 Vitamin B6 metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 91 258 5.56E-37
Gene3D G3DSA:3.30.1370.170 - IPR038251 PdxB, dimerisation domain superfamily 293 380 6.7E-29
Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. IPR020921 Erythronate-4-phosphate dehydrogenase 1 363 44.965473
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 277 4.6E-15
FunFam G3DSA:3.40.50.720:FF:000093 Erythronate-4-phosphate dehydrogenase - - 92 257 2.5E-75
PANTHER PTHR42938 FORMATE DEHYDROGENASE 1 - - 33 274 1.2E-36
SUPERFAMILY SSF52283 Formate/glycerate dehydrogenase catalytic domain-like - - 5 103 1.45E-15
Gene3D G3DSA:3.40.50.720 - - - 92 257 1.9E-118
Gene3D G3DSA:3.40.50.720 - - - 1 277 1.9E-118
CDD cd12158 ErythrP_dh IPR020921 Erythronate-4-phosphate dehydrogenase 2 350 0.0
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 107 256 7.6E-35
Pfam PF11890 Domain of unknown function (DUF3410) IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain 289 376 2.5E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.