Pseudomonas aeruginosa PA7, PSPA7_2596 (serS)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004812	aminoacyl-tRNA ligase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00587	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006418	tRNA aminoacylation for protein translation	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00587	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004828	serine-tRNA ligase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006434	seryl-tRNA aminoacylation	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00414	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000166	nucleotide binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00414	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PA7 genes in this class Translation, post-translational modification, degradation Other PA7 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
MetaCyc		L-selenocysteine biosynthesis II (archaea and eukaryotes)	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	pap00970	Aminoacyl-tRNA biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00981	Seryl-tRNA synthetase signature	IPR002317	Serine-tRNA ligase, type1	278	291	7.7E-34
PRINTS	PR00981	Seryl-tRNA synthetase signature	IPR002317	Serine-tRNA ligase, type1	318	331	7.7E-34
NCBIfam	TIGR00414	JCVI: serine--tRNA ligase	IPR002317	Serine-tRNA ligase, type1	1	419	0.0
Hamap	MF_00176	Serine--tRNA ligase [serS].	IPR002317	Serine-tRNA ligase, type1	1	424	41.366226
PIRSF	PIRSF001529	Ser-tRNA_ligase	IPR002317	Serine-tRNA ligase, type1	1	426	0.0
Coils	Coil	Coil	-	-	75	95	-
SUPERFAMILY	SSF55681	Class II aaRS and biotin synthetases	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	116	423	3.73E-102
PRINTS	PR00981	Seryl-tRNA synthetase signature	IPR002317	Serine-tRNA ligase, type1	335	351	7.7E-34
Coils	Coil	Coil	-	-	30	50	-
PANTHER	PTHR43697	SERYL-TRNA SYNTHETASE	-	-	1	425	0.0
Gene3D	G3DSA:3.30.930.10	Bira Bifunctional Protein; Domain 2	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	105	425	0.0
SUPERFAMILY	SSF46589	tRNA-binding arm	IPR010978	Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm	1	112	4.81E-31
Pfam	PF00587	tRNA synthetase class II core domain (G, H, P, S and T)	IPR002314	Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)	218	402	1.8E-35
Gene3D	G3DSA:1.10.287.40	-	IPR042103	Serine-tRNA synthetase, type1, N-terminal domain superfamily	1	104	6.8E-31
PRINTS	PR00981	Seryl-tRNA synthetase signature	IPR002317	Serine-tRNA ligase, type1	266	278	7.7E-34
PRINTS	PR00981	Seryl-tRNA synthetase signature	IPR002317	Serine-tRNA ligase, type1	353	369	7.7E-34
CDD	cd00770	SerRS_core	IPR033729	Serine-tRNA ligase catalytic core domain	119	419	0.0
Pfam	PF02403	Seryl-tRNA synthetase N-terminal domain	IPR015866	Serine-tRNA synthetase, type1, N-terminal	1	107	1.6E-30

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.