Pseudomonas aeruginosa PA7, PSPA7_0984 (ampC)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_0984
Name	ampC
Replicon	chromosome
Genomic location	987337 - 988530 (- strand)

Cross-References

RefSeq	YP_001346370.1
GI	152987941
Entrez	5353514
INSDC	ABR85124.1
NCBI Locus Tag	PSPA7_0984
UniParc	UPI0000D72888
UniProtKB Acc	A6UZY5
UniProtKB ID	A6UZY5_PSEA7
UniRef100	UniRef100_A6UZY5
UniRef50	UniRef50_Q1LMH1
UniRef90	UniRef90_A0A086C2H6

Product

Feature Type	CDS
Coding Frame	1
Product Name	beta-lactamase
Synonyms
Evidence for Translation
Charge (pH 7)	7.89
Kyte-Doolittle Hydrophobicity Value	-0.242
Molecular Weight (kDa)	43370.0
Isoelectric Point (pI)	9.47

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
PDC-33	PDC-33 is a PDC beta-lactamase. []	ARO:3006699	protein homolog model		Perfect	800.0	100.0	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 267 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001588 (493 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_0984 Search term: ampC Search term: beta-lactamase

Human Homologs

References