Pseudomonas aeruginosa PA7, PSPA7_0737 (pdxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050570 4-hydroxythreonine-4-phosphate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04166
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0042823 pyridoxal phosphate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00536
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00750 Vitamin B6 metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00557 JCVI: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA IPR005255 PdxA family 5 324 3.6E-128
Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase 2 327 36.362907
Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA IPR005255 PdxA family 31 320 1.1E-109
PANTHER PTHR30004 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE IPR005255 PdxA family 3 326 4.3E-116
Gene3D G3DSA:3.40.718.10 Isopropylmalate Dehydrogenase - - 1 328 0.0
SUPERFAMILY SSF53659 Isocitrate/Isopropylmalate dehydrogenase-like - - 3 327 4.57E-114

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.