Pseudomonas aeruginosa PA7, PSPA7_0513

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00088
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PA7 genes in this class
Chemotaxis Other PA7 genes in this class
Two-component regulatory systems Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1346 1444 9.15318E-16
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2122 2140 1.4E-10
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 2025 2161 1.7E-16
MobiDBLite mobidb-lite consensus disorder prediction - - 599 629 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1508 1630 3.01E-26
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2066 2080 1.4E-10
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1027 1113 3.2E-11
MobiDBLite mobidb-lite consensus disorder prediction - - 970 1019 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1346 1479 1.4E-28
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1168 1288 3.53E-14
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 433 556 1.18E-14
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 850 932 1.1E-13
MobiDBLite mobidb-lite consensus disorder prediction - - 645 674 -
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 2339 2451 1.5E-27
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1837 1976 1.3E-11
Coils Coil Coil - - 232 252 -
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 848 972 5.63E-27
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1656 1764 4.45E-20
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 2339 2450 2.59278E-30
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1025 1148 1.19E-18
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1656 1760 4.94304E-13
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1169 1297 1.1E-12
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1657 1750 4.4E-15
Coils Coil Coil - - 1354 1374 -
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1978 2159 7.99E-36
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1508 1606 1.67397E-15
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 2337 2450 2.9E-37
Coils Coil Coil - - 1738 1765 -
Coils Coil Coil - - 1875 1895 -
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1655 1752 2.2E-4
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1025 1116 1.89899E-5
CDD cd16916 HATPase_CheA-like - - 1984 2159 1.10385E-83
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1542 2457 0.0
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1510 1609 1.1E-14
Gene3D G3DSA:3.40.50.2300 - - - 2339 2458 6.2E-40
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1975 2161 9.9E-53
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1508 1605 0.0011
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 2021 2162 1.3E-22
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1508 1637 2.8E-27
SMART SM00260 chew_2 IPR002545 CheW-like domain 2154 2304 9.0E-35
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 98 1.5E-6
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 2336 2455 4.55E-36
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1977 2161 1.7E-60
MobiDBLite mobidb-lite consensus disorder prediction - - 560 581 -
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1025 1128 0.43
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1346 1443 4.0E-10
MobiDBLite mobidb-lite consensus disorder prediction - - 1471 1505 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1656 1780 2.6E-23
MobiDBLite mobidb-lite consensus disorder prediction - - 1761 1780 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 2146 2159 1.4E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1346 1468 4.32E-27
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 848 978 1.1E-28
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 848 945 6.2E-7
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 2161 2300 1.7E-21
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 2242 2302 2.9E-19
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 848 944 1.29005E-10
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 137 3.7E-10
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.57E-21
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1348 1441 9.7E-15
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1019 1153 1.5E-17
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 2167 2306 1.6E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.