Pseudomonas aeruginosa PA7, PSPA7_0502 (pyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016597 amino acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016743 carboxyl- or carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004070 aspartate carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PA7 genes in this class
Nucleotide biosynthesis and metabolism Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pap00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF53671 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 17 321 9.56E-95
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 276 281 3.4E-31
Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 170 317 1.1E-22
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 150 161 7.7E-18
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 92 101 3.4E-31
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 284 307 7.7E-18
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 149 166 3.4E-31
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 272 281 7.7E-18
Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 18 162 2.8E-41
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 150 306 1.2E-83
FunFam G3DSA:3.40.50.1370:FF:000006 Aspartate carbamoyltransferase - - 19 152 7.0E-73
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 235 244 3.4E-31
Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. IPR002082 Aspartate carbamoyltransferase 17 321 41.753513
PANTHER PTHR45753 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL - - 14 319 2.5E-64
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 19 315 1.2E-83
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 64 83 7.7E-18
FunFam G3DSA:3.40.50.1370:FF:000007 Aspartate carbamoyltransferase - - 153 306 1.6E-68
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 54 76 3.4E-31
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 300 314 3.4E-31
NCBIfam TIGR00670 JCVI: aspartate carbamoyltransferase IPR002082 Aspartate carbamoyltransferase 18 319 5.7E-90

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.