Pseudomonas aeruginosa UCBPP-PA14, PA14_70940 (betA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00732
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019285 glycine betaine biosynthetic process from choline
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008812 choline dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc choline degradation IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc glycine betaine biosynthesis II (Gram-positive bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.560.10 Glucose Oxidase, domain 3 - - 45 474 0.0
Pfam PF00732 GMC oxidoreductase IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal 5 302 2.6E-95
PANTHER PTHR11552 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE IPR012132 Glucose-methanol-choline oxidoreductase 4 541 0.0
SUPERFAMILY SSF54373 FAD-linked reductases, C-terminal domain - - 297 479 3.24E-64
NCBIfam TIGR01810 JCVI: choline dehydrogenase IPR011533 Oxygen-dependent choline dehydrogenase 6 539 0.0
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 1 537 1.37E-87
PIRSF PIRSF000137 Alcohol_oxidase IPR012132 Glucose-methanol-choline oxidoreductase 1 540 0.0
Pfam PF05199 GMC oxidoreductase IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal 395 529 2.2E-42
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 6 527 0.0
Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. IPR011533 Oxygen-dependent choline dehydrogenase 3 556 64.868187

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.